• The Neurobiology of Recovery of Naming Impairments
Adults with language disturbances following a stroke are needed for a research study that investigates language disorder due to stroke. The study involves two parts: 1) a brain imaging part and 2) a language testing part. You may also be asked to take part in a third part of the study involving treatment sessions.

The brain imaging part of the study involves monitoring activity of the brain while performing language tasks. In order to measure brain activity, you will be asked to lie inside a magnetic resonance (MR) scanner. These scans take place at the Athinoula A. Martinos Center for Biomedical Imaging (MGH East) in Charlestown, MA and last about 1.5 – 2 hours each. You will be asked to take part in three scan sessions with two scans per session over a 6-month period. You will be paid $100 for each scan, with a $50 bonus if you complete the study.

The language testing part of the study involves 7-10 visits of one to two hours each over the 6-month period of the study. These visits will take place at the Aphasia Research Lab at Boston University. During these visits you will do language tasks verbally and on a computer.

If you are asked to take part in the third part of the study, you will be also be asked to make up to 20 visits to the Aphasia Research Lab at Boston University (2 visits per week for up to 10 weeks). The treatment will focus on helping you to improve naming of items.

If you are not asked to take part in the treatment as part of the study, you will be offered this same treatment, free of charge, upon completion of the other parts of this study. You will also have the opportunity to take part in more MRI scans and language testing after the treatment is completed, over the course of another 6 months. If you take part in those scans and tests, you will be paid $100 for each MRI scan you take part in, and will receive a $250 bonus if you complete all parts of the study. If you do not want to take part in these scans and tests, you can still receive the free treatment.

In order to participate, you must be: 35-80 years of age, right-handed, and need to have learned English by age 12. You also must have difficulty with language following stroke.

Please call 617-807-0536 or email MGHNeuropsych@partners.org to confirm your eligibility if you think you qualify. We have a quick phone screening process to check your eligibility for the study and answer any questions you have about the study.
Institution  –  MGH - Massachusetts General Hospital, Boston, MA
Principal Investigator  – David N Caplan, MD, PhD
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name  – Jennifer J Michaud, CRC
Phone  – 617-807-0536