This research study aims to assess the effectiveness of lifestyle modification and drug treatment on HIV associated Metabolic Syndrome. Metabolic syndrome is a cluster of characteristics such as high blood pressure, high cholesterol, large waist circumference, and insulin resistance. Lifestyle modification, including monitored exercise sessions and dietary counseling, and the drug metformin are two strategies that are likely to improve the health status of individuals with HIV associated Metabolic Syndrome.
In the study, patients will be randomly selected (that is assigned by chance) to undergo an intensive lifestyle modification program and/or drug therapy. The potential benefits from this study include improved overall body composition, cardiovascular (heart/blood vessel) health, glucose tolerance, and insulin metabolism related to HIV associated Metabolic Syndrome. Subjects will be compensated for their time and effort with up to $300. Subjects randomized to the lifestyle modification group will receive an additional $240 allowance to help them maintain their healthy lifestyles.

Institution  –  MGH - Massachusetts General Hospital, Boston, MA; MIT, Cambridge, MA

Principal Investigator  – Steven K Grinspoon, MD

  

For further information about enrolling a patient in this trial, contact the person below.

Name  – Kathleen Fitch, NP

Phone  – 617-724-8015