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  • EndoBarrier: a Novel therapy for type 2 Diabetes in Obese adults (The ENDO Trial)
Type 2 Diabetes: The EndoBarrier Study

• Do you have type 2 diabetes?
• Do you take only oral medications to treat it?
• Are you overweight?
• Are you age 21-65?

If yes, you could be eligible for a study of a new, investigational device to lower blood sugar and help with weight loss. The EndoBarrier device is a thin, flexible, tube-shaped liner that forms a physical barrier between the food you eat and a portion of the intestinal wall. Study subjects are randomly assigned to receive either the device, which is placed endoscopically (a non-surgical procedure) in the small intestine or to have a sham procedure.

Subjects come to 10-12 study visits over 12-18 months and receive, at no cost:

• Diabetes medical management by study doctors
• Blood tests, chest X-ray, EKG
• Nutrition counseling for diabetes and weight control

Compensation for time and travel expenses is provided

For more information, please call Laurie Bissett, MS RDN at 617-726-1687
MGH Diabetes Research Center
Institution  –  MGH - Massachusetts General Hospital, Boston, MA
Principal Investigator  – Enrico Cagliero, MD
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name  – Laurie Bissett, CRC
Email  –
Phone  – 617-726-1687

About Obesity:
Being obese increases the risk for many diseases, especially heart disease, stroke, cancer, and diabetes.

According to the Centers for Disease Control and Prevention, obesity has reached epidemic proportions. It has a far-ranging negative effect on health. Persons who are overweight or obese are at increased risk for developing many different health conditions, including heart disease, type 2 diabetes, and bone and joint disease.