• Autoimmunity: In Vitro Pathogenesis and Early Detection
The Faustman Lab, under the direction of Denise Faustman, MD, PhD, is currently leading a human clinical trial program testing the efficacy of the BCG (Bacillus Calmette-Guérin) vaccine for treatment of long-term type 1 diabetes, translated from her diabetes reversal work in end-stage mice that was first reported in 2001.

We are currently preparing for a detailed immune screening and characterization of pancreas decay of long-term diabetics that might qualify for the upcoming Phase II of our clinical trial.

We are looking for type 1 diabetics over the age of 16 to come to our lab for a 30 minute visit. A blood sample will be taken during this visit.

If you are interested, please contact Elise Hsu or Menghan Zhao at 617-726-4084 or diabetestrial@partners.org for more information. You may also visit our website at www.faustmanlab.org.
Institution  –  MGH - Massachusetts General Hospital, Boston, MA; Massachusetts General Hospital - East, Charlestown, MA; Faustman Clinical Program, Charlestown, MA
Principal Investigator  – Denise Faustman, MD, PhD
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name  – Menghan Zhao, CRC
Phone  – 617-726-4084

About Type 1 Diabetes:
Type 1 diabetes accounts for 5 to 10 percent of all diagnosed cases of diabetes in the US. Type 1 diabetes usually develops in children or young adults, but can start at any age. It may also be known by a variety of other names, including the following:
  • insulin-dependent diabetes mellitus (IDDM)
  • juvenile diabetes
  • brittle diabetes
  • sugar diabetes
There are two forms of type 1 diabetes:
  • idiopathic type 1 diabetes - refers to rare forms of the disease with no known cause.
  • immune-mediated diabetes - an autoimmune disorder in which the body's immune system destroys, or attempts to destroy, the cells in the pancreas that produce insulin. Immune-mediated diabetes is the most common form of type 1 diabetes, and the one generally referred to as type 1 diabetes. The information on this page refers to this form of type 1 diabetes.