• Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)
Type 2 Diabetes Treatment: the GRADE Study

Do you have type 2 diabetes?
Have you had it for ten years or less?

If you answered “yes” to these questions, you may be eligible to join GRADE, a research study seeking to learn the best combination of medicines to treat type 2 diabetes.

Study subjects are randomly assigned (by chance, like the toss of a coin) to take the diabetes medicine metformin plus one other diabetes medication. All medications -- and combinations of medications -- used in GRADE are commonly prescribed and are approved by the FDA to treat type 2 diabetes.

If you join GRADE, you will:
• Be given brief physical assessments, and diabetes care, education, medication and supplies at no cost.
• Be seen 4 times a year at the MGH Diabetes Center for diabetes treatment.
• Be in the study for 4 to 7 years, depending on when you join.
• Receive $100 per year for your time and free parking at MGH parking garages.

Study doctors will manage your diabetes care in coordination with your regular health care provider.

To find out more, contact Mike Yepes
phone: 617-643-7737
email: GRADE@partners.org
or visit https://grade.bsc.gwu.edu.
Institution  –  MGH - Massachusetts General Hospital, Boston, MA
Principal Investigator  – Deborah Wexler, MD
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name  – Mike Yepes
Email  – GRADE@partners.org
Phone  – 617-643-7737

About Type 2 Diabetes:
Type 2 diabetes is a metabolic disorder resulting from the body's inability to make enough, or to properly use, insulin. It used to be called non-insulin-dependent diabetes mellitus (NIDDM).
Without adequate production or utilization of insulin, the body cannot move blood sugar into the cells. It is a chronic disease that has no known cure. It is the most common type of diabetes, accounting for 90 to 95 percent of diabetes cases.