• Inflammatory Cellular Trafficking in Asthma in response to Segmental Allergen Challenge: Substudy:A pilot study to assess the distribution of regulatory T cells (Tregs) in the peripheral blood of patients with severe asthma
As part of our ongoing NIH-sponsored asthma research, a "substudy" has been created to investigate the level of regulatory T cells in the blood of severe asthma patients and healthy controls. This substudy is IRB approved. The title of the study is: "A pilot study to assess the distribution of regulatory T cells (Tregs) in the peripheral blood of patients with severe asthma". We would appreciate your assistance in recruiting healthy control volunteers that are preferably over the age of 45, for the study. The study involves a single visit during which we will:

- collect basic demographic and general health information
- perform a pregnancy test (women only)
- review the inclusion/exclusion criteria for the study
- document medication usage
- perform a simple spirometry
- measure exhaled nitric oxide (very simple technique, less effort than spirometry)
- obtain 50 MLs of blood

Participants do not need to be fasting. We anticipate that this study will take 30-40 minutes. We plan to conduct visits on Monday morning between 7:30 - 9 AM in the Allergy Associates Clinic. There is a $30 compensation for your participation.

If interested please call 617-724-8256 and ask about The Severe Asthma
Substudy.
Institution  –  MGH - Massachusetts General Hospital, Boston, MA
Principal Investigator  – Andrew D Luster, MD, PhD
  
Enrollment Information
For further information about enrolling a patient in this trial, contact the person below.
Name  – Lloyd L Liang, CRC
Phone  – 617-724-8256