Note: This study is currently only recruiting patients in the hospital.
If you are interested in being notified if this study begins recruiting from the general population, please use the 'I Am Interested' button below.
Try Bezafibrate - a new treatment drug for Bipolar Depression
Enrollment for this study is expected to close on Saturday, January 25, 2025
Overview
What we are studying
We are studying the effectiveness of Bezafibrate, a drug that lowers fat, in treating bipolar depression.
Why it is important
Bipolar disorder is among the top causes of disability worldwide and negative health outcomes remain highly prevalent. Only 20% to 30% of bipolar patients achieve remission from a mood episode and even then, remain stable for two years. New drug development for bipolar disorder, and especially bipolar depression, has generally stalled in the past decade, with few new methods of treatment and no treatments developed specifically for bipolar disorder. Investigating whether Bezafibrate can be an effective drug treatment for bipolar depression can help improve patient outcomes.
What we hope to accomplish
We hope to determine the effectiveness of the novel drug treatment, Bezafibrate, in treating bipolar depression and expanding treatment options for Bipolar Disorder.
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Principal Investigator
Project Contact
Click I Am Interested "I Am Interested" "I Am Interested" to get started. If you have questions, contact:
Broghan O'Hearn
Clinical Research Coordinator
Hadi Kobaissi
Who can participate
Who cannot participate
Diagnosed with Bipolar Disorder ot otherwise specified (NOS), Schizoaffective Disorder, Substance Use disorders in the past 3 months, Schizophrenia, delusional disorders or psychotic disorders, Borderline or antisocial personality disorder, or OCD-spectrum disorders
What you may be asked to do
Project activities may include:
- Survey
- Blood draw
- Medication
- Office visit
- MRI scan
- Biopsy
Estimated Time Commitment
6 visits over 10 weeks
What You May Get
All subjects will be provided with parking reimbursement and receive 8 weeks of medication treatment at no cost. If attending each study visit as scheduled, participants will be paid $300 at the end of the study. Participants involved in the MRI component of the study will also receive $50 for each scan, up to $100 total.
Location
Travel
- Parking reimbursed
Travel and Parking Details
Additional Information
Study Phase
Phase 1: This project studies the safety of a medication or treatment, usually on healthy volunteers. It examines the medication or treatment’s effects on the body and looks for side effects.
Funding Source
- Foundation